Frankenhooker

Director:  Frank Henenlotter

Year:  1990

Plot:  A medical student sets out to recreate his decapitated fiancee by building her a new body made of Manhattan street hookers.

A personal fave of mine Frankenhooker has it all.  mad scientists, super crack, exploding prostitutes, and a pimp named Zorro.  what's not to love.  Definitely one of my top ten favorite horror comedies ever made.